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These metabolites can exert either neuroprotective effects or neurotoxic effects

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[Abstract]2024 Jul 1:829:111873

Endothelial activation and blood-brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells

FIGURE 1 2 The role of sleep in regulating free radicals in the brain: from Reimunds free radical flux theory to modern insights Reimunds free radical flux theory of sleep, proposed in the 1990s, received significant attention for suggesting that ROS accumulate in the brain during wakefulness, when energy consumption is high, and are subsequently cleared during sleep through a scavenging process that also suppresses their production (Reimund, 1994

The other half is the discovery that homocysteine damages your arteries, brain and DNA itself