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Another element that plays a role in myelopathies caused by B12 deficiency is the disturbance of neuronal lipid and protein synthesis, which includes fundamental elements such as myelin proteins that create myelin sheaths in the spinal cord and peripheral nervous system (PNS) [83]

Methylation analysis of CGG sites in the CpG island of the human FMR1 gene

10.1002/jor.23195 173 WalkerB

It should not be assumed to be present in every patient

Spectra for assignment of 15 N/ 13 C-labelled CEP192 sample (100 M, 20 mM (K/H) 3 PO 4 , 150 mM NaCl, 0.5 mM TCEP, 2% glycerol, 5% D 2 O) were recorded on a 750 MHz Oxford Instruments Spectrometer equipped with a 5 mm Bruker TCI cryoprobe and a Bruker Avance III HD console, with data acquisition achieved using Topspin

Treatment protocol The adult male Wistar rats (n = 40) were assigned to eight groups (n = 5/group) and treated daily with intraperitoneal drug injections for seven days as follows: Group 1 (Control) was administered water (0.2 mL/day), while groups 24 were administered NAC at doses of 25, 50, and 100 mg/kg, 20 respectively