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Proteins linked to neutrophil degranulation are more abundant in patients with AH compared to AUD and controls and are associated with disease severity

The observed upregulation potentially indicates that N , N -dimethylglycine may play a role in the pathophysiology of these conditions, particularly in more severe manifestations of PE

Van Bavel N, Issler T, Pang L, Anikovskiy M, Prenner EJ

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Our preliminary interpretation is that replacement of Tyr110 indeed affects the interaction with GSH but, as compared to K105A/Y, does not drastically alter the ratio between the steady-state concentrations of the deprotonated and glutathionylated enzyme species E and F, respectively

The 8-OHdG concentrations in both the CSF and blood were significantly higher in PD patients than in the normal subjects, with higher concentrations in non-demented PD patients