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We thoroughly discussed the bidirectional role of ferroptosis in radiotherapy, providing new strategies and insights for improving tumor radiotherapy sensitivity and reducing radiation-induced injury in clinical practice

In vivo studies may be constrained by variations in genetic origins, environmental circumstances, and disease progression in animal models and humans

This intricate relationship highlights the complex mechanisms at play in the cellular response to environmental challenges, shedding light on the adaptive strategies employed by organisms to survive and thrive in changing conditions

The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction

The cerebrovascular adaptations to RT are supported by work from Thomas et al, who conducted 12 weeks of progressive RT (progression from 60%90% 1RM with repetitions lowering as intensity increases, 3 times per week) in healthy young adults and similarly observed increased cerebrovascular resistance and decreased pulsatility at rest

Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver