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Key Takeaways Glutamate is the primary excitatory neurotransmitter in the brain Glutamate binds to both ionotropic (AMPA, NMDA, and kainate) receptors and metabotropic receptors GABA is the primary inhibitory neurotransmitter in the brain Glycine is the primary inhibitory neurotransmitter in the periphery GABA and Glycine bind to ionotropic receptors that open chloride channels Test Yourself

Thus, this pathway must function on a continuous basis to function efficiently, and requires the constant presence of adequate glutathione as well as the formation of methylcobalamin

Vitamin B12 injections are also commonly used to help relieve fatigue

Statistical analysis was performed by repeated measurement of ANOVA and Bonferroni post hoc test and/or contrast analysis of compared groups

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