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However, high-quality research needs to be done to determine the impact of vitamin B12 itself on weight loss

This commenter proposed excluding: (1) patients without email or text messaging access, (2) patients who have not given (or have withdrawn) prior consent for text message survey invitations (to comply with the TCPA), and (3) patients who requested confidential admission (to adhere to HIPAA)

3.3 Quality and bias risk assessment The methodological quality of the included studies was independently assessed by two reviewers using the Cochrane Risk of Bias Tool for Randomized Trials (RoB 2)