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Furthermore, the PfGrx-catalyzed oxidation of roGFP2 is more than four orders of magnitude faster than the uncatalyzed reaction with GSSG and occurs two orders of magnitude faster via the glutathione-dependent monothiol mechanism than by the glutathione-independent dithiol mechanism (Fig

Scarano, V

Oxford University Press

In the past, it has also been employed in the treatment of biliary dyskinesia and chronic abdominal pain in neurological conditions (Crile, 1951

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The role of Ca(2+) in cell death caused by oxidative glutamate toxicity and ferroptosis