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Other strategies need to be employed to help control homocysteine

The evidence base requires appropriate clinical trials, with additional endpoints including clinical symptoms of patients and additional biochemical parameters beyond plasma B12 levels alone before these alternative routes can be recommended with confidence in clinical guidelines

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Brown K, DeCoffe D, Molcan E, Gibson DL

10.1016/j.yexcr.2017.11.021 Exp Cell Res

Additionally, exploring the route through which MPO penetrates the parenchymal functional cells of target organs in autoimmune disorders via the cell membrane necessitates in-depth exploration