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Furthermore, while biological agents targeting specific inflammatory pathways have demonstrated promising clinical outcomes, approximately 3050% of patients either fail to respond initially or develop neutralizing antibodies that diminish therapeutic effectiveness over time

Its been shown to enhance the pathogen-fighting effects of monocytes and macrophages, which are immune cells

Yudhistira, B., Mutia, A

Finally, through gel-shift assays using a ubiquitin activity-based probe we demonstrate on-target engagement with UCHL3 in two cell lines