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Gut 72 , 10931100 (2022)

Although a 2004 Cochrane review found insufficient evidence to support the use of these antivirals alone, 15 two recent placebo-controlled trials demonstrated full recovery in a higher percentage of patients treated with an antiviral drug in combination with prednisolone than with prednisolone alone (100 percent versus 91 percent and 95 percent versus 90 percent)

It accomplishes this by using protecting groups around the amino acids of GHRH typically susceptible to enzymatic degradation, thus increasing the half-life