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Inhibition of AURKA markedly attenuates the proliferative and migratory potential of Cal27 and CNE2 cell lines

Hammond C, Babbitt WR, Mohan RK

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Bree Foster Arrowhead's RNAi drug cuts triglycerides by up to 81 percent and eliminates pancreatitis risk in highest-risk patients Arrowhead Pharmaceuticals announced positive topline results this week from two global Phase 3 trials SHASTA-3 and SHASTA-4 of plozasiran, an RNA interference (RNAi) therapy that silences apolipoprotein C-III (APOC3), a liver-produced protein that drives triglyceride accumulation