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In addition, inflammation induces cyclo-oxygenase-2 (COX-2) expression, thus enhancing prostaglandin (PGE) synthesis [7]

Here, point mutations were introduced within key consensus motifs within the APP tail (previously described in Janurio et al, 2022) and their binding was validated by immunoblotting

In addition, LA protected cortical neurons against A peptide- and hydrogen peroxide-induced damage, suggesting that the neuroprotective effects were partly related to PKB/Akt signaling pathway stimulation (Zhang et al., 2001)

p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice

Along with GSTs, some of these enzymes offer additional routes by which ascorbate and, particularly, glutathione can be linked to peroxide metabolism

Alterations of Brain and Cerebellar Proteomes Linked to A and Tau Pathology in a Female TripleTransgenic Murine Model of Alzheimer's Disease. Cell Death & Disease 1: e90