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Dysregulation of Pin-1 has been associated with cancers and Alzheimers disease (reviewed in Guito and Lukac, 2015)

Interestingly, Peleg and colleagues found that old mice have deregulated H4K12ac levels in certain key genes, impairing their ability to learn (Peleg et al., 2010)

soluble CLIC1 undergoes a transition to a membrane-bound form through oligomerization followed by the formation of an intramolecular disulfide bond (Cys24-Cys59) 12,14

doi: 10.1517/14740338.2.4.347 207 HPG

(6718:) Xaa-Pro aminopeptidase 1 (X-Pro aminopeptidase 1) (X-prolylaminopeptidase1, soluble) (Cytosolic aminopeptidase P) (Solubleaminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase)

for instance, 26 was of firmer binding energy than pipernigramide F 32 owing to the only difference between them, which was the side chain length