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CFS is a pathological condition characterized by profound disabling fatigue lasting more than 6 months and is associated with infectious, rheumatological, and neurological symptoms

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When administered intravenously, NAC has also proved invaluable in the treatment of acetaminophen overdose

Sumi T, Harada K

Several investigational agents capable of inhibiting NLRP3 activation, such as tranilast, 354 dapansutrile (OLT1177, selective inhibitor), 354 and thiazolo-alkenyl sulfonylurea derivative 7, 355 are also being considered for COVID-CS treatment as reviewed by Freeman and Swartz

Addressing these limitations will be crucial in translating this approach into a clinically viable therapy