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The normal cellular function of C9orf72 is related to vesicular trafficking and autophagy (Farg et al., 2014) whereas SOD1 is an antioxidant enzyme that mediates detoxification of the superoxide anion radical (

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Methylation decreases in response to moderate folate depletion in elderly women

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Similarly, the small molecule USP24-i-101 facilitates autophagy-dependent PD-L1 degradation and may help mitigate acquired resistance to ICIs (140)

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Acrolein plays a significant role in contributing to oxidative stress through the generation of ROS [4]

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