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Remarkably, a 5- to 10-milliliter dose of either compound, when administered to an adult of average weight, could sustain plasma concentrations up to 20 times higher than the desired threshold levels for several hours (Pace et al., 2002)

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Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer

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The adenosine triphosphate (ATP)-dependent 26 S assays were performed using 100 M ATP in the absence and presence of a specific proteasome inhibitor: 10 M bortezomib (5 activity) and 100 M bortezomib (1 and 2 activities)

Overall, the literature data from mainly experimental and clinical studies suggest that bilirubin is a molecule of immunological importance that shows a protective effect in inflammatory and autoimmune diseases