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In summary, the use of immune agonists and TME-modulating agents not only amplifies immediate effector responses but also, more importantly, orchestrates the immune system toward the establishment of durable AIM, a paradigm shift essential for overcoming adaptive resistance in cancer immunotherapy

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Front Psych 4:130 Lowin T et al

Lengeler C

This finding underscores the intricate interplay between iron homeostasis and mitochondrial function and the induction of pyroptotic cell death