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Emerging evidence suggests that ME/CFS, GWS, and FM are all characterized by disturbances in metabolic pathways, particularly those related to energy production, lipid metabolism, and oxidative stress

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IgG = the antibody immunoglobulin G

Outinen PA, Sood SK, Liaw PCY, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, and Austin RC (1998)

Thirdly, patients with Down syndrome or autism have increased oxidative stress and exhibit particular disturbed profiles of one-carbon metabolism [1315]