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Ferroptosis is a phospholipid peroxidation-driven mode of regulated cell death [11]

Dubost NJ, Beelman R, Peterson D, Royse DJ

There is also a connection between glutathione and gaseous mediators such as hydrogen sulfide and nitric oxide, that are involved in the regulation of the functioning of the cardiovascular system

Challenges in any of these steps could result in low protein expression, while the inherent properties of the molecule itself may limit its production via mechanisms such as cytotoxicity or inherent instability