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In contrast, IDH-mutant gliomas convert -KG into 2-HG (2-hydroxyglutarate), which disrupts normal metabolic processes and epigenetic regulation, resulting in slower tumor progression and greater therapeutic sensitivity [22]

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Long-distance turgor pressure changes induce local activation of plant glutamate receptor-like channels

[DOI] [PubMed] [Google Scholar] 28.Garcia-Romeu A, Cox DJ, Smith KE, Dunn KE & Griffiths RR Kratom ( Mitragyna speciosa ): user demographics, use patterns, and implications for the opioid epidemic