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Li C, Deng D, Jiang Q, Shi J, Xu L, Liu Y

DavisSAItamanSKhalid-JanneyCMSherardJADowellJACairnsNJet alTDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

Fact: Your body thrives on balance

It also processes toxins and hormones, metabolizes B vitamins, and regulates neurotransmitters

After one month, rats in the high-sugar, high-fat diet groups were given a single intraperitoneal injection of STZ (40 mg/kg), while the control group received an equivalent volume of sodium citrate buffer

Also, both mutant and WT SOD1 produce cytotoxic levels of H 2 O 2 via a cysteine redox regulation system (Bakavayev et al., G93A mice show significantly increased protein carbonyl levels in the spinal cord, including elevated carbonylation of mutant SOD1, which has been linked to motor neuron degeneration (Poon et al., 2005)