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In older children with mild disease, a 1 mg daily oral treatment regimen is suggested ( The different recommended doses, formulations and treatment schedules both between and within these countries highlight the important disparity in international clinical practice for the treatment of this heterogenous condition

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Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 4), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification

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Regulatory status Not FDA-approved for any use