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Di Gioacchino, M

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Tsai PY, Zhang B, He WQ, Zha JM, Odenwald MA, Singh G, Tamura A, Shen L, Sailer A, Yeruva S, et al

[73] demonstrated that MK8722 activates the upstream autophagy pathway PI3K/Akt/mTOR, downregulating FASN expression in a dose-dependent manner, and inhibits downstream autophagy by blocking the fusion of autophagosomes and lysosomes, leading to epithelial ovarian cancer cell death

JAMA Network Open 7(2):e240260, 2024

Complement and microglia activation mediate stress-induced synapse loss in layer 2/3 of the medial prefrontal cortex in male mice

System xc serves as an amino acid reverse transporter that orchestrates the exchange of extracellular cystine and intracellular glutamate across the cell membrane [77]