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Dasari S, Gonuguntla S, Yellanurkonda P, Nagarajan P, Meriga B (2019) Sensitivity of glutathione S-transferases to high doses of acrylamide in albino wistar rats: Affinity purification, biochemical characterization and expression analysis

We propose that IOP elevation initiates hypoxia that contributes to mitochondrial dysfunction, oxidative stress, impaired mitophagy and inflammation and that these processes are exacerbated by interactions between inflammation and mitochondrial dysfunctional (Figure 1)