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Signal Transduct Target Ther 7(1):95 Tomuleasa C, Tigu AB, Munteanu R, Moldovan CS, Kegyes D, Onaciu A et al (2024) Therapeutic advances of targeting receptor tyrosine kinases in cancer

Chao WH, Askew EW, Roberts DE, et al

B.PortoM

Cancer cells may be exploiting a common antioxidant as fuel, revealing a potential weakness that future therapies could target

3.2 HIF Pathway Hypoxia Inducible factors (HIFs) are transcription factors, consisting of an oxygen-labile subunit (HIF-) and a constitutively stable subunit (HIF-), which play pivotal roles in inducing cellular responses to hypoxia and in regulating immune cell effector functions (95, 96)