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While the study volunteers were older adults, who may have a specific vulnerability to lower levels of B12, co-first author Alexandra Beaudry-Richard, MSc, said that these lower levels could impact cognition to a greater extent than what we previously thought, and may affect a much larger proportion of the population than we realize. Beaudry-Richard is currently completing her doctorate in research and medicine at the UCSF Department of Neurology and the Department of Microbiology and Immunology at the University of Ottawa

A retrospective external validation set from an additional three European cohorts (n = 7,025), four Japanese hospitals (n = 281) and two hospitals from the USA (n = 1,437) was established

Rather than following conventional three-meal-a-day patterns, many people find that smaller, more frequent meals for example, four to five modest portions spread throughout the day are far better tolerated and help maintain consistent energy levels