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The PM(2.5) concentration of 100 g/mL was chosen for subsequent experiments

Am J Physiol Regul Integr Comp Physiol 294:R311R320 Datz C, Muller E, Aigner E (2017) Iron overload and non-alcoholic fatty liver disease

The excess iron is stored in the iron storage protein complex composed of ferritin light chain polypeptide and ferritin heavy chain polypeptide 1, and the remaining part of Fe 2+ will be oxidized to Fe 3+ and transferred out of cells to participate in iron renewal in the body cycle ( 2+ level in cells is a key factor for lipid peroxidation and induction of ferroptosis, and TF-mediated iron uptake or iron autophagy can increase its level ( Lipid Metabolism and ROS Lipids are important regulators of cell death

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doi: 10.1007/s40256-017-0249-9 35 HosseinimehrS

10.1016/j.gene.2020.145066 185 ZhangJ