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Description

The SLN is the first lymph node to receive lymphatic flow from a tumor, and thus is often an early site of metastasis in many cancer types ( Nodal micrometastases (NMM) have been associated with a worse prognosis in NSCLC

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If the GPCR requires the presence of one of the G-proteins for functional expression in HEK-293 cells, all subsequent experiments are performed with HEK-293 cell cotransfected with the GPCR and the G-protein which gives the best response

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