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As we proposed at 428.203(b), CMS will remove from the total number of units any units of a generic drug dispensed on or after the date that such generic drug no longer meets the definition of a Part D rebatable drug, as well as units acquired through the 340B Program, as described in section III.I.3.c.iv.2

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When NNMT is inhibited: NAD+ levels rise Mitochondria become more efficient Cells burn more energy, even at rest This effect helps the body shift into a more metabolically active state, making it easier to reduce fat and preserve muscle during weight loss