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GSH activity is facilitated by activation of the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 that regulates expression of genes controlling antioxidant, inflammatory and immune system responses

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Pre-treatment with LFP-20 facilitated a balanced Th1 and Th2 response, which is consistent with the modulation of Th1 cytokines (IL-12p70, IFN-, and TNF-) and Th2 cytokines (IL-4, IL-5, and IL-6) (99)

Hyperpigmentation and Uneven Skin Tone By controlling melanin synthesis, glutathione helps reduce dark spots, tanning, and patchy pigmentation