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Chinese Pharmacolog Bulletin

Isatuximab binds to a specific epitope that partially encompasses, but does not block access to or alter the configuration of the CD38 ectoenzyme catalytic site [11, 20]

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Harrington KJ, Champiat S, Brody JD, Cho BC, Romano E, Golan T, et al

When pretreating the cells with N -ethylmaleimide (NEM, 20 mM), a trapping reagent of thiol species, for 0.5 h, the signals from the cytoplasmic regions are decreased in both green and yellow channels (Figure 7DF)