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DHAR and GR activities convert the DHA translocated from the lumen and the DHA generated in the stroma to AsA (Asada, AsA-GSH pathway in mitochondria The presence and activity of AsA-GSH cycle enzymes in mitochondria of plant cells have been established, and this cycle plays an important role in protecting mitochondrion against the toxic ROS regularly produced in respiratory chain reactions (Leonardis et al., 2000

Moreover, disease progression in these trials may be too advanced to regain sufficient mitochondrial and therefore target cellular function

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Establishing a sustainable routine that you can maintain for months is more valuable than aggressive short-term protocols

The first involves fibroblast activity, angiogenic processes, nitric oxide-related signalling and tissue response to experimental conditions