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In oxidative homeostasis, this pathway seems to be central in different cells (232234)

Ostry V, Malir F, Toman J, Grosse Y

Also, bad reactions are rare

A clinical assessment of hyperandrogenism can rely on a modified Ferriman-Gallwey score designed to measure hirsutism, where a high score is associated with elevated free testosterone, but this test is limited to one symptom which is not specific to PCOS