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Efficacy was assessed among all randomized participants regardless of treatment discontinuation or rescue intervention

We recommend refrigerating the product after opening to ensure it remains fresh and effective for as long as possible

The lipophilic property per se does not oppose the clinical use of the respective compounds, because lipophilic substances could exert neuroprotective function thanks to their ability to penetrate within cellular membranes [124]

LLOQ, lower limit of quantification

effect on fistula closure

It is essential for: Mitochondrial energy production (ATP) DNA repair and cellular resilience Activation of sirtuins , proteins involved in metabolism and healthy aging Redox balance , helping cells respond to metabolic stress NAD levels naturally decline with age and may be lower in people with metabolic disease, chronic inflammation, or prolonged stress