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Sestrin2 plays a protective role in AD by mitigating Ang II-induced VSMC cell apoptosis through the Nrf2 pathway (161)

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the E.coli cytosine deaminase gene or one of the thymidine kinase genes from Herpes Simplex Virus, Cytomegalovirus and Varicella-Zoster virus, in which case ganciclovir may be used as prodrug to kill the IL-10 transgenic cells in the subject (see e.g