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"The message from this research is that women should quit smoking before becoming pregnant, or very early on, to reduce the chance of having a baby with a serious and lifelong physical defect." Co-author, Professor Charles Rodeck, UCL Institute for Women's Health, added: "The results of this research are of the greatest significance for the health of mothers and babies and for public health policy

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Through the interwar years, studies by Franz Hermann Muller and others laid the groundwork for the case against smoking, though American doctors would take until the 1950s to duplicate, confirm, and publicize the findings

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First, fuel economy varies naturally week to week based on driving routes, traffic, weather, passenger load, and driver behavior