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270 Thus, the relationship among PS1 gene mutations or deficiencies, lysosomal acidification, and lysosomal calcium ion dysregulation warrants further investigation

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The inhibition of phosphorylation of Stat1 Ser727 is related to transcriptional Nrf2 inhibition Crizotinib-induced Stat1 phosphorylation at Ser727 and Tyr701 sites, but their individual roles in regulating ferroptosis were unclear