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The role of mitochondrial dysfunction in Huntingtons disease: implications for therapeutic targeting

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Mitochondrial fission and fusion: a dynamic role in aging and potential target for age-related disease

16 It has been shown that influenza viruses induce oxidative stress mediated by an excess of ROS and a decrease of reduced glutathione, and that such conditions favour viral replication, with glutathione depletion pivotal for the folding and maturation of the viral glycoprotein and therefore viral replication

This makes perfect sense as erythrocytes take up large amounts of sphingosine and detoxify this sphingolipid by enzymatic conversion to sphingosine-1-phosphate by sphingosine kinase [124]