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By binding to c-Met, Dihexa activates signaling pathways that promote neuronal survival and potently improve cognitive function

Through these mechanisms, BPC-157 has been explored in research examining the coordination between vascular signaling, cellular migration, and structural tissue recovery

Most promisingly, we could successfully soak in and solve crystal structures with the NMR hit 27 and several of its analogues to fully characterise the binding modes within this fragment hit series

10.1073/pnas.192399699 Proc Natl Acad Sci USA

This translates to approximately 1.6 to 4 mcg per kilogram of body weight, extrapolated from effective rat doses using standard interspecies scaling factors