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Advanced methods such as single-cell sequencing and spatial transcriptomics have been used to map detailed gene expression and pathway networks for each cell in the retinal microenvironment during the development of AMD (416)

Cisplatin with or without rucaparib after preoperative chemotherapy in patients with triple negative breast cancer: final efficacy results of Hoosier Oncology Group BRE09-146

Abbreviations 5-HD: 5-hydroxydecanoate AMPK: AMP-activated protein kinase ETC: Electron transport chain G-6-P: Glucose-6-phosphate Glut-1: Glucose transporter 1 LPS: Lipopolysaccharide MnSOD: Manganese superoxide dismutase MRS: magnetic resonance spectrum mtDNA: Mitochondrial DNA nDNA: Nuclear DNA NO: nitric oxide NOS: nitrogen species NRF-1: Nuclear respiratory factor-1 NRF-1/2: nuclear respiratory factors 1 and 2 OXPHOS: Oxidative phosphorylation PGC-1: PRAR-coactivator-1 PMN: Polymorphonuclear neutrophil rhTFAM: Recombinant human TFAM ROS: Reactive oxygen species TFAM: Mitochondrial transcription factor A TPP: Triphenylphosphonium VDACs: Voltage dependent anion channels References Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al

Copper, ceruloplasmin and superoxide dismutase in patients with Alzheimers disease: A case-control study

2022;8:eabm6393

219 For example, Wang et al