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This indicates the need for further optimization of the pharmacokinetics of different administrative routes and treatment paradigm for improved long-lasting effects

The SPR results suggest that the RBD dimer interacts with the chimeric mFc-ACE2 receptor similarly to the RBD monomer

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A hundred l PreScission protease (GE Healthcare Life Sciences) solution containing 50 mM Tris (pH 8.0), 100 mM NaCl, 1 mM EDTA, 1 mM DTT was added to the column and incubated for 12~16 hr at 4 C, and then 3MST, which had been excised from GST-fusion, was recovered by centrifugation at 735 g for 1 min at room temperature

Injectable BPC-157 is administered via subcutaneous injection, while oral BPC-157 is taken in capsule form

Western blot density quantification was performed using ImageJ software 36 and are displayed in Supplementary Fig