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Background Up to 95% of menstruating individuals experience period pain, with estimates ranging from 4595%, and nearly one in three lose work or school days when symptoms peak

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Patients report feeling full on 1,2001,500 calories daily without conscious restriction

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Additionally, the accumulation of ROS can disrupt mitochondrial function, resulting in a loss of mitochondrial membrane potential and the release of pro-apoptotic factors like cytochrome c and AIF into the cytosol, which activates the caspase cascade and causes DNA fragmentation, leading to apoptosis

74,75 Given that the majority of tissues and organs in diabetic patients are affected by hyperglycemia-induced oxidative stress, using natural products with anti-diabetic and antioxidant abilities may have several positive impacts