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Bian Q, et al

Notably, C2-ceramide has been shown to induce a rapid reduction in mitochondrial membrane potential

Since the concentration of antioxidants is low in the sperm cytoplasm, protection against ROS is provided by GPx5 only (Taylor et al

Curcumin Suppresses Soluble Tau Dimers and Corrects Molecular Chaperone, Synaptic, and Behavioral Deficits in Aged Human Tau Transgenic Mice. Journal of Biological Chemistry 288: 40564065

While canonical GSTs conjugate GSH with electrophilic compounds, the subclasses theta, phi and tau have also been shown to act as GSH-dependent peroxidases that release GSSG [50, 51]

Therefore, the present invention provides a method whereby hypoxic tissue can be treated so as to quickly regain and maintain normal ATP levels, both to improve tissue survival and to hasten general bodily recovery