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3) for the development of LNPs, with several innovative designs of microfluidic systems being evaluated to improve the mixing and/or dilution of the lipid and nucleic acid solutions while achieving strong encapsulation efficiency and transfection (Billingsley et al., 2020

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

MIAT lncRNA was found to sponge miR-22-3p in a DM rat model, and its upregulation in DCM promoted excessive cardiomyocyte apoptosis (148)

Polese B, Zhang H, Thurairajah B, King IL

Various studies confirmed an association between Parkin and oxidative stress

These genes further demonstrate strong associations with immune cell infiltration, m6A RNA methylation, FRG expression, and chemotherapeutic sensitivity (Zhang et al., 2024a)