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As the mitral valve degenerates, the valve no longer fully closes after each pumping action, allowing some blood to flow backwards through them from the ventricle back into the atrium

This leads to a reduced ability of the heart to pump blood effectively, causing a range of health issues, like reduced exercise tolerance, arrhythmias (irregular heartbeats) and congestive heart failure, where fluid builds up in the lungs or abdomen

Vitamin B5 additionally contributes to normal mental performance (EFSA)

Peer review Peer review information Nature Reviews Cancer thanks Dong Gao and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Additionally, a single in vitro fertilization (IVF) attempt also failed

If youre pregnant, theres a 1 in 5 chance youll experience restless leg syndrome in the last 3 months of your pregnancy