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doi: 10.1038/s41467-021-26131-z

This condition differs from tolerance, which is the need for increasing doses of opioids to maintain a defined effect (see Dependence)

On the other side, inflammation provides various molecules essential to the formation of a microenvironment suitable for tumor development

4.5.4 Therapeutic strategies targeting ferroptosis in AD Given the strong association between ferroptosis and AD, targeting this pathway presents a promising approach for disease intervention

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Some tumor cells use "redox remodeling" to raise the antioxidant system to a high level to balance with the threat and obtain a chance of survival (Yang et al., 2016)