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Additionally, treatment with the essential oil enhanced Akt kinase phosphorylation, with partial inhibition observed using the PI3K/Akt inhibitor (LY294002), indicating the involvement of the PI3K/Akt pathway

According to the observations, Se compounds (both organic and inorganic compounds, as well as Se-NPs), were able in most cases to suppress cell proliferation and migration, and induce oxidative stress and apoptosis, both of which are considered to underlie antitumor effects of Se in general (122)

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doi: 10.1186/s12876-016-0540-2

male, n = 40