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Cell viability Resazurin reduction assay Resazurin (Sigma) was added to the cell culture medium (5 g/ml) for a period of at least 30 min

In agreement with in vitro findings, DMF treatment induced the expression of Cbs, Ahcy, and NRF2 targets such as Gclc, Gclm, and Slc7a11, but not that of Cse (Fig

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To evaluate the PK properties, the GLP-1 albumin fusions were administered to human FcRn Tg32 mice by IV injections, and blood samples were collected for up to 12 days (Fig

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