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Cisplatin (Figure 9c) and Etoposide (Figure 9d) treatments also replicated these effects: siScramble spheroids showed moderate architectural disruption, whereas siE6/E7 and siVangl1 spheroids exhibited fragmented contours, loss of central density, significantly dissociated cells, reduced size and a halo of cell debris

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The indirect comparison method was used to manually screen relevant literature by reviewing abstracts and discussions

7,64 For instance, CKD patients may develop low or high sodium levels due to imbalances in sodium excretion and retention