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Mounting evidence suggests that ferroptosis liabilities are frequently imposed by the tumor microenvironment, metastatic niche and nutrient availability, implying that conventional in vitro models may underestimate therapeutic opportunities

Our aim is to conduct a screening study using the HADS and HAM-D questionnaires to detect anxiety and depressive symptoms in the early post-stroke period

doi: 10.3390/MA12040641 123 Muoz-BonillaA.Fernndez-GarcaM

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Here, we review recent advances linking UPS components with specific human diseases, most prominently cancer and neurodegenerative disorders, and emphasize potential sites of therapeutic intervention along the regulated protein-degradation pathway

NHEK was cultured in KBM2 supplemented with 0.4% bovine pituitary extract, 0.33 g ml 1 hydrocortisone, 0.39 g ml 1 epinephrine, 10 g ml 1 transferrin and 1.8 mM CaCl 2 , with or without hHGF or dimeric macrocycle